MK BIOTECH

Limitations of Global Pharmaceutical Companies' Development of New Drugs

Although there were successful cases in preclinical trials using mice, more than 85% failed in early clinical trials.
Waste of mice in preclinical trials.
Lack of experimental animals due to medium-to-large sized preclinical trials.

A Dog as Disease Model Animal

A relatively longer life expectancy compared to mice.
Share similar biological mechanisms with humans and
have the same genetic diseases.
Dogs and cats are the only animals with Alzheimer’s
Disease and Parkinson’s Disease
Command and behavior control are possible, therefore,
cognitive/motor ability analysis and
evaluation are possible for brain function evaluation.

Alzheimer's disease Disease Model Animals for Alzheimer’s Disease Research: Alzheimer's disease is the most common degenerative neurological disease that causes dementia and deteriorates memory and cognitive function. Using genetic scissors technology and somatic cell nuclear transplantation technology, disease model animals can be developed, and through this, it can be used for research on pathogenesis and new drug development.

Parkinson's disease Disease Model Animals for
Parkinson’s Disease Research

In Parkinson’s disease, the abnormal functioning of a neurotransmitter in the brain, ‘dopamine’, causes slow movement, tremors, and stiff muscles which cause physical disabilities. In animals, it is only identified in dogs and cats

Confirmation of dopamine secretion abnormalities through PET-CT scans.